Center for Stem Cell and Translational Immunotherapy (CSTI)

Brigham and Women's Hospital, Harvard Medical School

Publications 2017 – 2015

2020 thru 2018| 2017 | 2016 | 2015 | 2014 thru 2010 | 2009 thru 2005 | 2004 thru 2001 


Lobbardi R, Pinder J, Martinez-Pastor B, Theodorou M, Blackburn JS, Abraham BJ, Namiki Y, Mansour M, Abdelfattah NS, Molodtsov A, Alexe G, Toiber D, de Waard M, Jain E, Boukhali M, Lion M, Bhere D, Shah K, Gutierrez A, Stegmaier K, Silverman LB, Sadreyev RI, Asara JM, Oettinger MA, Haas W, Look AT, Young RA, Mostoslavsky R, Dellaire G, Langenau DM.  TOX Regulates Growth, DNA Repair, and Genomic Instability in T-cell Acute Lymphoblastic Leukemia.  Cancer Discovery. 2017 doi: 10.1158/2159-8290.CD-17-0267 PMID: 28974511

Du W, Seah I, Bougazzoul O, Choi G, Meeth K, Bosenberg MW, Wakimoto H, Fisher D, Shah K. Stem cell-released oncolytic herpes simplex virus has therapeutic efficacy in brain metastatic melanomas. PNAS  USA. 2017 doi: 10.1073/pnas.1700363114. PMID: 28710334

Choi SH, Stuckey DW, Pignatta S, Reinshagen C, Khalsa JK, Roozendaal N, Martinez-Quintanilla J, Tamura K, Keles E, Shah K. Tumor Resection Recruits Effector T Cells and Boosts Therapeutic Efficacy of Encapsulated Stem Cells Expressing IFNβ in Glioblastomas. Clinical Cancer Research. 2017 doi: 10.1158/1078-0432.CCR-17-0077. PMID: 28912136

Ignatius MS, Hayes MN, Lobbardi R, Chen EY, McCarthy KM, Sreenivas P, Motala Z, Durbin AD, Molodtsov A, Reeder S, Jin A, Sindiri S, Beleyea BC, Bhere D, Alexander MS, Shah K, Keller C, Linardic CM, Nielsen PG, Malkin D, Khan J, Langenau DM. The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma. Cell Reports 2017 doi: 10.1016/j.celrep.2017.05.061. PMID: 28614716

Jahan N, Lee JM, Shah K, Wakimoto H. Therapeutic targeting of chemoresistant and recurrent glioblastoma stem cells with a proapoptotic variant of oncolytic herpes simplex virus. International Journal of Cancer. 2017  doi: 10.1002/ijc.30811. PMID: 28567859

Zhu Y, Bassoff N, Reinshagen C, Bhere D, Nowicki MO, Lawler SE, Roux J, Shah K. Bi-specific molecule against EGFR and death receptors simultaneously targets proliferation and death pathways in tumors. Scientific Reports. 2017 doi: 10.1038/s41598-017-02483-9. PMID: 28572590


Shah K. Stem cell-based therapies for tumors in the brain: are we there yet? Neuro Oncology. 2016 doi: 10.1093/neuonc/now096. PMID: 27282399

Choi SH and Shah K. Engineered bifunctional proteins and stem cells: Next generation of targeted cancer therapeutics Discovery Medicine 2016 Sep;22(120):157-166. PMID: 27755970


Zhu, Y., Choi, SH. and Shah, K. Multifunctional receptor-targeting antibodies for cancer therapy. Lancet Oncology. 2015 doi: 10.1016/S1470-2045(15)00039-X. PMID: 26545843

Bagci-Onder T, Du W, Figueiredo JL, Martinez-Quintanilla J, and Shah K. Targeting breast to brain metastatic tumors with death receptor ligand expressing therapeutic stem cells. BRAIN 2015 doi:10.1093/brain/awv094. PMID: 25910782

Choi SH, Tamura K, Khajuria RK, Bhere D, Nesterenko I, Lawler J, and Shah K. Antiangiogenic Variant of TSP-1 Targets Tumor Cells in Glioblastomas. Molecular Therapy. 2015 doi: 10.1038/mt.2014.214. PMID: 25358253

Martinez-Quintanilla J, He D, Wakimoto H, Alemany R, and Shah K. Encapsulated Stem Cells Loaded With Hyaluronidase-Expressing Oncolytic Virus for Brain Tumor Therapy. Molecular Therapy 2015 doi: 10.1038/mt.2014.204. PMID: 25352242

Stuckey D, Hingtgen SD, Karakas N, Rich BE, and Shah K. Engineering toxin-resistant therapeutic stem cells to treat brain tumors. Stem Cells. 2015 doi: 10.1002/stem.1874. PMID: 25346520

Redjal N, Zhu Y, and Shah K. Combination of systemic chemotherapy with local stem cell delivered S-TRAIL in resected brain tumors. Stem Cells. 2015  doi: 10.1002/stem.1834. PMID: 25186100

Bhere D and Shah K. Stem Cell-Based Therapies for Cancer. Advances in Cancer Research. 2015 doi: 10.1016/bs .acr.2015.04.012. PMID: 26093900

Wehrenberg-Klee E, Redjal N, Leece A, Turker NS, Heidari P, Shah K, and Mahmood U.PET imaging of glioblastoma multiforme EGFR expression for therapeutic decision guidance.American Journal of Nuclear Medicine and Molecular Imaging. 2015 Jun 15;5(4):379-89. eCollection 2015. PMID: 26269775

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